My wife is looking for a replacement for her 2006 Lexus RX330. For a year I felt the MKC was our perfect choice. Seeing and driving the MKC for the first time changed that. I really wanted to like the MKC, but it had too many strikes against it. For my wife, the first thing that killed the deal was the headrest that couldn't be adjusted back far enough. She loved the way it drove, but the cargo space compared to her RX was strike two. For me, the back seat room was strike three. I'm 5'11" and it was an effort that shouldn't have existed to get in, and especially out, of the rear seats.
This past weekend we drove the 2015 Murano and we both loved it. For less money we can get more of everything. It is extremely comfortable, front and back, with very good cargo space. The only aspects that will be missed are the MKC's real wood trim and better mileage.
I'm a very happy Fusion Hybrid owner and wanted to support Ford. As was stated earlier, the Murano really has to be compared to the MKX, but then the price difference is really substantial. My wife is very hard to please and really wants another Lexus, but after driving it she says she'll be very happy with the Murano.